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U.S. Patent Number : 5,536,506
USE OF PIPERINE TO INCREASE THE BIOAVAILABILITY OF NUTRITIONAL COMPOUND
Date of Patent : July 16, 1996
Inventors : Muhammed Majeed, Vladimir Badmaev, R. Rajendran
Assignee : Sabinsa Corporation, Piscataway, NJ
ABSTRACT: Compositions and methods for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the compositions compromise a minimum of 98% of pure alkaloid piperine. The method comprises oral, topical, or parenteral administration of the compositions of the invention. A new process for the extraction and purification of piperine is also disclosed.

U.S. Patent Number : 5,744,16
USE OF PIPERINE AS A BIOAVILABILITY ENHANCER
Date of Patent : April 28, 1998
Inventors : Muhammed Majeed, Vladimir Badmaev, R. Rajendran
Assignee : Sabinsa Corporation, Piscataway, NJ
ABSTRACT: Compositions and methods for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the compositions compromise a minimum of 98% of pure alkaloid piperine. The method comprises oral, topical, or parenteral administration of the compositions of the invention. A new process for the extraction and purification of piperine is also disclosed.

U.S. Patent Number : 5,972,382
USE OF PIPERINE AS A BIOAVILABILITY ENHANCER
Date of Patent : October 26, 1999
Inventors : Muhammed Majeed, Vladimir Badmaev, R. Rajendran
Assignee : Sabinsa Corporation, Piscataway, NJ
ABSTRACT: Compositions and methods for the improvement of gastrointestinal absorption and systemic utilization of nutrients and nutritional supplements, wherein the compositions compromise a minimum of 98% of pure alkaloid piperine. The method comprises oral, topical, or parenteral administration of the compositions of the invention. A new process for the extraction and purification of piperine is also disclosed.

U.S. Patent Number : 6,054,585
PROCESS FOR MAKING HIGH PURITY PIPERINE FOR NUTRITIONAL USE
Date of Patent : April 25, 2000
Inventors : Muhammed Majeed, Vladimir Badmaev
Assignee : Sabinsa Corporation, Piscataway, NJ
ABSTRACT: The present invention relates to a process of making high purity piperine for nutritional and nutraceutical application. This process recovers piperine from piperine-containing oleoresin by using isourea, urea or a urea derivative to remove organic matter other than piperine from the oleoresin. Preferably, the process recovers piperine from oleoresin of fruit of piper nigrum or piper longum. More preferably, the process recovers piperine from oleoresin of fruit of piper nigrum, i.e. black pepper.

European Patent Number : 0810868
USE OF PIPERINE AS A BIOAVAILABILITY ENHANCER
Applicant : Sabinsa Corporation
In post-opposition phase waiting for official issuance.

Japanese Patent Number : Pending H-525650
USE OF PIPERINE AS A BIOAVAILABILITY ENHANCER
Applicant : Sabinsa Corporation

Canadian Patent Number : Pending - Application: No. 2,247,467
USE OF PIPERINE AS A BIOAVAILABILITY ENHANCER
Applicant : Sabinsa Corporation

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