ChromeMate® Shown to Ameliorate Symptoms of Syndrome X

Metabolic Syndrome (Syndrome X) is a cluster of risk factors, including obesity, greater abdominal fat, insulin resistance, hypertension and blood lipid abnormalities. Metabolic Syndrome has been linked to the development of type 2 diabetes, cardiovascular disease and aging. Maintaining optimal insulin and blood sugar metabolism has been reported to slow the aging process in laboratory animals. This study examined the effects of three supplements in animals that develop features of Metabolic Syndrome and diabetes with age. Three groups of older rats were supplemented with ChromeMate®, Super CitriMax®, or a maitake mushroom fraction for 6 weeks, while a fourth group served as controls. During the final 3 weeks, a group was given a combination of all three supplements and compared to untreated animals. All three supplemented groups showed significantly lower systolic blood pressure, as well as less free radical damage in liver and kidney tissues over the initial 6 weeks.

During that period, body weight significantly declined in control animals a decline that is characteristic of these animals during the later stages of failing health. In contrast, both the ChromeMate® and maitake supplements largely prevented this anticipated loss. The Super CitriMax® group also lost weight, though fewer experienced a greater than average drop compared to controls. Most importantly, treatment with the combined supplements resulted in a lower systolic blood pressure and better body weight maintenance overall. Results from other experimental studies in younger insulin-resistant animals as well as clinical trials show that ChromeMate®, Super CitriMax® or maitake can favorably alter many risk factors associated with Metabolic Syndrome. The findings from this study suggest that dietary supplements of ChromeMate®, Super CitriMax® and maitake may also benefit people with diabetes, as well as the elderly.

Source: Talpur N, Echard BW, Yasmin T, Bagchi D, and Preuss H, Effects of Niacin-Bound Chromium, Maitake Mushroom Fraction SX and (-)Hydroxycitric Acid on the Metabolic Syndrome in Aged Diabetic Zucker Fatty Rats, Molecular and Cellular Biochemistry, 252:369-377, 2003.