Acute Toxicity Study at St John’s National Academy of Health Sciences, India

An acute toxicity study on Wistar rats was done, under OECD guidelines, using a very high dose of 5 g per kg body weight. No mortality or toxicity was observed.

No mortality was observed following the administration at a very high dose of 5g/kg body weight. Body weight, feed and water intake in all the rats were comparable with that of the control.

Subchronic Oral Toxicity Study at Bombay College of Pharmacy, India

A Subchronic Toxicity Study was done in Wistar Rats, under OECD guidelines, at 90 mg per kg bodyweight, which is equivalent to the recommended human dosage of 1 gram a day. No mortality or toxicity was observed.

Mutagenicity Study [ Ames Test ] at Intox Pvt. Ltd., India

Mutagenicity Study by Salmonella Typhimurium reverse mutation test was carried out as per the OECD guidelines. It was concluded that the product was non-Mutagenic in all the 5 strains of Salmonella Typhimurium.

The Toxicity studies on Slimaluma® were presented at the 2006 Annual Meeting and Exposition of the American Association of Pharmaceutical Chemists in San Antonio, Texas, USA, held from 29th October to 2nd November 2006.