Phytochemistry

Updated: May 26 2009

Forskolin ( 7ß-acetoxy-8,13-epoxy-1a,6bß,9a-trihydroxylabd- 14-en11-one) is a diterpenoid compound which directly activates adenylate cyclase.

Other diterpenoids, deacetylforskolin, 9-deoxyforskolin, 1,9-deoxyforskolin, 1,9-dideoxy-7-deacetylforskolin, along with four minor diterpenoids have also been reported to be present in the roots of Coleus forskohlii.

References

Tandon, J.S. et al. (1977) Ind. J. Chem., 15B : 880-883.
Gabetta. B., et al. (1989) Minor diterpenoids of Coleus forskohlii Phytochemistry, 28(3):859-862.

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