Gugulipid
What is Gugulipid®?
Gugulipid® is a standardized extract prepared from the oleogum resin (gum resin) of Commiphora mukul, an Indian medicinal tree that has been clinically proven to reduce the levels of harmful serum lipids in the bloodstream. The active ingredients responsible for the maintenance of healthy cholesterol levels are the guggulsterones, specifically guggulsterone E and guggulsterone Z.
- Hyperlipidemia (High Cholesterol):Terminology
- Commiphora mukul: The Plant Source of Gugulipid®
- Phytochemistry of Commiphora mukul
- Gugulipid® - Mechanism(s) of Action
- Importance of Proper Analytical Methodology and the 10% Gugulipid ® Myth
- Traditional Uses and Contemporary Significance to Health
- Safety and Toxicity
- Sabinsa Studies On Gugulipid®
- Recommended Dosage
- Gugulipid® Products from Sabinsa
- Contact Sabinsa
Research and Studies
- Pre-Clinical Trial Research
- Second Pre-Clinical Trial Research
- Third Pre-Clinical Trial Research
- Clinical Study
- Further Studies and Research
Pre Clinical Trial 1
The objective of this research is to study the effect of C. mukul on the prevention and regression of hypercholesterolemia in rabbits.
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Pre Clinical Trial 2
The objective of this research is to investigate the hypocholestrolemic effects of an alcoholic extract of C. mukul.
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Pre Clinical Trial 3
The objective of this research is to study the lipid lowering activity of gugulipid in various animal models.
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Clinical Studies
Clinical Studies on the effect of Gugulipid on serum cholesterol levels of hyperlipidemic patients.
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Further Studies
Open Field Study to Evaluate Gugulipid in the Treatment of Dyslipidemias.
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Hyperlipidemia
Hyperlipidemia is a disorder characterized by abnormally high concentrations of lipids (fats) in the blood that are correlated with the development of atherosclerosis.
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Commiphora Mukul
Commiphora mukul is a small tree of the Burseraceae family that is indigenous to India.
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Phytochemistry of Commiphora mukul
Chemical investigations have focused on the oleogum resin of Commiphora mukul due to its hypolipidemic properties.
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Mechanism of Action
The studies on gum guggul indicate that its hypolipidemic activity can be attributed to more than one mechanism.
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Importance of Proper Analytical Methodology
It is probable that powdered guggul products which claim an active ingredient level in excess of 6.0% may be crude and unpurified extracts.
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Traditional Uses and Contemporary Significance to Health
The Atharva Veda is the earliest reference to the medicinal and therapeutic properties of guggul.
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Safety and Toxicity
A four-week, phase 1 (safety on chronic administration) study was conducted on 21 subjects with certain conditions.
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Sabinsa Studies On Gugulipid
Open Field Study to Evaluate Gugulipid in the Treatment of Dyslipidemias.
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Recommended Dosage
The recommended dose is the amount of Gugulipid equivalent to 25 mg of guggulsterones three times a day.
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Gugulipid Products
Sabinsa Corporation supplies Gugulipid Granules, Gugulipid 40 Mesh, and Gugulipid Soft Extract.
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Contact Sabinsa
Sabinsa Corporation contact information.
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