Contraindications

Animal model studies conducted on forskolin reported an extremely low order of toxicity ^1,2.
The acute LD50 values for forskolin in the mouse and rat models are (105 mg/kg i.p. & 3,100 mg/kg per oral) and (92 mg/kg i.p. & 2,550 mg/kg per oral), respectively³.
Although no major side effects have been reported, C. forskohlii should be avoided by gastric ulcer patients and low blood pressure cases. It should be used with caution by those on prescription medications, especially antiasthmatics and antihypertensives since C. forskohlii may potentiate the effects of these prescription drugs².

References

Murray, M.T. (1995) The unique pharmacology of Coleus forskohlii. Health Counselor 7(2): 33-35.
American Botanical Council. Coleus ForsLean Monograph. HerbClip May 1, 1997.
Agarwal, K.C. and Parks, R.E. (1983) Forskolin: A potential antimetastatic agent. Int. J. Cancer 32: 801-804.

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