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Clinical Studies

Author: Dr. Edward Group 05/26/2009
 

Blood Lipid Lowering Activity and Related Effects

Study 1

Phase II Clinical Studies conducted in India as shown below

Figure 16

Effect of Gugulipid on serum cholesterol levels of hyperlipidemic patients.

Figure 16

Figure 17

Effect of Gugulipid on the serum lipids of 7 patients with ischemic heart disease.

Figure 17

Figure 18

Effect of Gugulipid on serum lipids of 39 patients without ischemic heart disease.

Figure 18

Figure 19

Effect of Gugulipid on the HDL, LDL, and VLDL of patients without IHD.

Figure 19

Figure 20

Effect of Gugulipid on the HDL, LDL, and VLDL of patients with IHD.

Figure 20

Figure 21

Effect of Gugulipid on the serum cholesterol levels of hyperlipidemic patients.

Figure 21

Study 2

Objective: To study the effect of gum guggul on the serum fibrinolytic activity (FA) and platelet adhesive index (PAI).

Methods: Healthy subjects (20) and patients of coronary heart disease were divided into control and treated subgroups. The treated groups received a gum guggul fraction of 0.5 g twice daily in a gelatin capsule for 30 days. Withdrawn blood samples were analyzed for fibrinolytic activity and platelet adhesive index.

Results

Figure 22

Effect of gum guggul on the fibrinolytic activity of healthy subjects.

Figure 22

Figure 23

Effect of gum guggul on the fibrinolytic activity of CAD patients.

Figure 23

Figure 24

Effect of gum guggul on the platelet adhesive index in healthy subjects.

Figure 24

Figure 25

Effect of gum guggul on the platelet adhesive index in CAD patients.

Figure 25

Conclusions: The gum guggul fraction reduced platelet adhesiveness and increased the blood’s fibrinolytic activity (i.e. fibrin-breaking activity), two actions that are extremely beneficial in protecting against heart attack and stroke (thrombosis). The activity persisted as long as the gum guggul was taken.

Posted In: Gugulipid

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