ChromeMate® is a unique, patented form of biologically active niacin-bound chromium called chromium nicotinate or polynicotinate that dramatically increases the safety and effectiveness of chromium, an essential trace mineral required for normal insulin function.*

What is ChromeMate®?

ChromeMate® (generically called chromium nicotinate, chromium polynicotinate or niacin-bound chromium) is a patented oxygen-coordinated niacin-bound chromium complex that plays an important role in proper insulin function, maintenance of healthy blood sugar and cholesterol levels, normal energy production, and promotion of healthy body weight.* Protected by three U.S. Patents, four international patents and other world-wide patents pending, ChromeMate® is the only niacin-bound chromium supplement with proven biological activity.

What does ChromeMate® do?

Combined with exercise and a sensible diet, ChromeMate® helps:

• Maintain healthy body weight and promotes normal energy metabolism*
• Maintain healthy cholesterol levels and promotes cardiovascular health*
• Promote normal insulin function and maintains healthy blood sugar levels*

How does ChromeMate® work?

Chromium is at the heart of a biologically active complex called Glucose Tolerance Factor or "GTF", which is responsible for potentiating (increasing) the action of insulin in the body. Insulin is a vital hormone responsible for transporting glucose inside cells and maintaining proper blood sugar and blood lipid (cholesterol) levels in the body. Chromium helps insulin metabolize fat, turn protein into muscle and convert sugar into energy. In fact, chromium-activated insulin increases the amount of blood sugar available for energy production nearly twenty-fold.

A lack of chromium can result in type II diabetes, obesity and heart disease. Dr. Walter Mertz, former director of the U.S. Department of Agriculture's Human Nutrition Research Center, established that GTF chromium consists of chromium bound to the B-vitamin, niacin. ChromeMate® is a unique form of oxygen-coordinated niacin-bound chromium found to be 18-times more potent than other forms of niacin-bound chromium tested. Protected by three U.S. patents, four international patents and other world-wide patents pending, ChromeMate® is the only niacin-bound chromium supplement with proven biological activity.

How is ChromeMate® different?

ChromeMate® is a unique, patented niacin-bound chromium complex that significantly increases the bioavailability and biological activity of chromium. Studies have shown that ChromeMate® is 18-times more bioactive than other forms of niacin-bound chromium and, in animal models used to evaluate bioavailability in humans, is absorbed and retained more than 600% greater than chromium chloride and 300% greater than chromium picolinate.** Additional clinical (human) and sub-clinical (animal) studies have shown that ChromeMate® lowers serum cholesterol and improves HDL (good) cholesterol levels, lowers blood pressure, reduces body weight, increases lean body mass and promotes proper insulin function in the body. One study showed that ChromeMate® plus exercise in obese women resulted in significant loss of body weight, while chromium picolinate did not. Another study in obese human subjects showed that ChromeMate® reduced body fat, while sparing lean muscle mass.* For additional information on ChromeMate® research, click here.

**Results of six tissues tested one hour after administration. Absorption and retention decreased in all groups at each successive time point measured, but continued to be greatest in animals fed ChromeMate®.

How much ChromeMate® should I take?

The recommended adult daily dosage is 200-400 micrograms (elemental chromium as ChromeMate®) taken with a meal. For additional information on dosing, follow manufacturer's recommended use printed on the label and/or talk to your healthcare professional.

Where can I buy ChromeMate®?

ChromeMate® is a nutritional ingredient available in a wide variety of dietary supplements and nutraceutical food and beverage products. Most products can be found at your local health food store; otherwise you can order directly from the manufacturer. Look for the ChromeMate® logo on the label to be sure you're getting genuine ChromeMate®, niacin-bound chromium. Following is a list of companies and products that contain ChromeMate®:

Research and Studies

• ChromeMate® Improves Metabolic Disorders in Double-Blind Pilot Study
• ChromeMate® Shown to Improve Fasting Glucose Levels
• Protective Effects of ChromeMate® and Grape Seed Extract
• ChromeMate® Shown to Lower Blood Pressure and Insulin Levels in Animals
• ChromeMate® Shown to Help in Age-Related Metabolism
• ChromeMate® Shown to Ameliorate Symptoms of Syndrome X
• ChromeMate® Improves Performance in Elite Cyclists
• ChromeMate® and Maitake Mushroom Found to Significantly Reduce Body Weight, Blood Pressure and Fasting Blood Glucose Level in Rats
• ChromeMate® Plus Exercise Found to Reduce Weight in Obese Women
• ChromeMate® Found to Increase Fat Loss and Spare Lean Body Mass in Obese Women
• ChromeMate® Shown to Reduce Cholesterol Levels in Humans
• ChromeMate® Found to be More Bioavailable than Other Chromium Supplements Tested
• ChromeMate® and OptiZinc® Found to Reduce Signs of Aging
• Trace Elements May Reduce Aging Associated with Insulin Resistance
• ChromeMate®'s GRAS (Generally Recognized as Safe) Status